Cowesby is a village and civil parish in the Hambleton District of North Yorkshire, England. Part of the village including The Cowesby Hall Estate is within the North York Moors National Park and about 7 miles (11 km) north of Thirsk. The population of the civil parish was estimated at 70 in 2014.

The village is mentioned in the Domesday Book as being in the Allerton Hundred and listed as Cahosbi. At the time of the Norman invasion the lands were recorded as belonging to Edwin, Earl of Mercia, but were ceded soon afterwards to King William I, though the manor was in the hands of Hugh, son of Baldric.